9. Itchy skin
Excess bilirubin resulting from pancreatic cancer not only causes jaundice and dark colored urine, it can also cause skin symptoms such as itching, irritation and inflammation. The large amount of bilirubin ultimately finds its way onto the skin as bile salts leak through pores. This causes blistering rashes to form on various sites in the body.
Increased production of glucagon, an enzyme also produced by the endocrine glands of the pancreas, can also cause lesions on the skin that start out as red, itchy patches, with centrally-located blisters that break up to form crusts. These blisters heal and then reappear in other places, a cycle that is both uncomfortable and depressing for some patients.
If you notice an unusual rash that persists despite treatment and care, make sure to seek consultation with a healthcare professional as it could be a possible sign of pancreatic cancer.
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