{"id":5720,"date":"2023-08-01T04:01:01","date_gmt":"2023-08-01T04:01:01","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=5720"},"modified":"2023-08-01T04:01:01","modified_gmt":"2023-08-01T04:01:01","slug":"taking-common-pain-medications-may-increase-heart-failure-risk-in-type-2-diabetes-patients","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/taking-common-pain-medications-may-increase-heart-failure-risk-in-type-2-diabetes-patients\/","title":{"rendered":"Taking Common Pain Medications May Increase Heart Failure Risk In Type 2 Diabetes Patients"},"content":{"rendered":"
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Pexels<\/figcaption><\/figure>\n

People with Type 2 Diabetes (T2D)<\/a> face a higher risk of heart failure<\/a>. In fact, even without a heart disease diagnosis, they are considered to have double the risk of developing heart failure as compared to those in the general population, says previous research<\/a>.<\/p>\n

However, recent research indicates that the risk could be further elevated by the use of common pain medications, such as Advil or Motrin (ibuprofen<\/a>).<\/p>\n

A new study<\/a> published in the Journal of the American College of Cardiology<\/a> shows that the short-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) was linked to an increased risk of first-time hospitalization for people with type 2 diabetes.<\/p>\n

While NSAIDs are known to carry cardiovascular risks and are typically not recommended for people with known heart disease, this study suggests that extending this caution to individuals with type 2 diabetes, even without a heart disease diagnosis, might be prudent. However, experts point out that more research is still needed.<\/p>\n

People With Type 2 Diabetes Seem to Use NSAIDs More<\/strong><\/h3>\n

According to a Danish study of over 330,000 individuals with type 2 diabetes, the researchers found that 1 in 6 people filled out at least one NSAID prescription within one year.<\/p>\n

Lead author of the study, Anders Holt, MD<\/a>, of Copenhagen University Hospital<\/a> in Denmark, explained that this fact alone was worth taking note of.<\/p>\n

\u201cOne of the more surprising findings, to me, was the quite substantial use of prescribed NSAIDs in a population of patients with diabetes \u2014 a patient group with a well-established cardiovascular risk,\u201d<\/strong><\/em> says Dr. Holt.<\/p>\n

NSAIDs are Associated with 40% Increased Risk of Heart Failure<\/strong><\/h3>\n

Danish registries were used by investigators to identify people with TD2 between 1998 and 2021. The average age of the patients was 62 years old, while 44 percent were women. Excluded from the study were those diagnosed with heart failure or rheumatological condition requiring long-term NSAID use.<\/p>\n

In just the first year of their inclusion in the study, \u201816 percent of the subjects filled at least one NSAID prescription, while 3 percent filled at least three prescriptions.\u2019 Ibuprofen was found to be the most common at 12.2 percent, while diclofenac<\/a> was next at 3.3 percent. Then it was naproxen at 0.9 percent and celecoxib at 0.4 percent.<\/p>\n

Unlike the United States, research<\/a> shows that NSAIDs are quite commonly prescribed within Denmark instead of just purchased over-the-counter.<\/p>\n

During a median follow-up around six years after the trial began, over 23,000 study subjects were hospitalized due to heart failure for the first time.<\/p>\n

The utilization of NSAIDs was linked to a significant 40 percent increase in the relative risk of hospitalization for first-time heart failure. Upon conducting separate analyses for individual NSAIDs, it was found that diclofenac and ibuprofen usage showed an elevated risk of heart failure hospitalization, while celecoxib and naproxen did not exhibit such a correlation. This difference could possibly be attributed to the relatively low percentage of people obtaining prescriptions for celecoxib<\/a> and naproxen<\/a>.<\/p>\n

The researchers also looked at heart failure risk alongside NSAID use in particular subgroups of patients. This is what they found:<\/p>\n