{"id":5509,"date":"2023-06-30T06:36:07","date_gmt":"2023-06-30T06:36:07","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=5509"},"modified":"2023-06-30T06:36:07","modified_gmt":"2023-06-30T06:36:07","slug":"large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/","title":{"rendered":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke"},"content":{"rendered":"
\"\"
Pexels<\/figcaption><\/figure>\n

In a large trial, the results showed that just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation, as well as the risk of heart attack and stroke, by an impressive 58%, if they had heart failure.<\/p>\n

Statistics show that 6 million Americans have been clinically diagnosed with heart failure. This is a heart condition described as a lack of the heart\u2019s ability to pump blood through the heart and body sufficiently.<\/p>\n

As for study lead author, Dr. Emerson Perin, he told<\/a> the European Pharmaceutical Review, \u201cFor the first time, we\u2019ve discovered that stem cells can successfully treat the inflammation that causes heart failure.\u201d<\/strong><\/em><\/p>\n

Currently, this has been considered the biggest trial of cell therapy for heart disease, which demonstrated many several results. Moreover, the researchers note that one should understand the cure in order to truly understand the problem.<\/p>\n

One is considered to have heart failure when less than 40% of the blood inside the heart gets pumped out into the body. In theory, one could suffer a cardiovascular event, such as a heart attack, at any time. This is called left ventricular ejection fraction (LVEF)<\/a>, while a healthy person\u2019s fraction sits between 55% to 70%.<\/p>\n

Inflammation is highly associated with heart disease, since both of these health condition tend to arise from a poor lifestyle pattern, causing most of the heart disease cases. As a result, the cardiologists from the Texas Heart Institute created a treatment that could address the inflammation.<\/p>\n

They decided to take stem cells from a patient\u2019s bone marrow, which is called mesenchymal precursor cells, and replicate them in a lab through proprietary methods. This injection, which was developed by a pharmaceutical company called Mesoblast, was then injected straight into a patient\u2019s heart.<\/p>\n

This kind of treatment, which is called rexlemestrocel-L, was well-tolerated by most patients, and for those that received it, they didn\u2019t have any additional inflammation as a result. Moreover, the patients that were treated also showed increased performance<\/a> of LVEF, meaning their hearts managed to pump out more blood volume than before.<\/p>\n

As explained in a statement by CEO of Mesoblast, Dr. Silviu Itescu, \u201cWe are very encouraged by these study data that indicate the potential of our allogeneic cellular therapy to address the major areas of unmet need in heart failure patients where conventional treatments are not effective.\u201d<\/strong> <\/em><\/p>\n

\u201cImprovement in LVEF at 12 months may be a functional surrogate endpoint for rexlemestrocel-L\u2019s subsequent benefits on long-term MACE outcomes and survival in this high-risk patient population with chronic heart failure,\u201d<\/strong><\/em> he added.<\/p>\n

The trial has since been placed on a phase 3, double-blinded, placebo-controlled trial status, which is considered the \u201cgold standard\u201d for medicine. The hope is that it will open the door for future trials of the same type of medication, which turning the research into real treatments for the thousands of people suffering from heart disease.<\/p>\n

\n","protected":false},"excerpt":{"rendered":"

In a large trial, the results showed that just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation, as well as the risk of heart attack and stroke, by an impressive 58%, if they had heart failure. Statistics show that 6 million Americans have been clinically diagnosed with […]<\/p>\n","protected":false},"author":9,"featured_media":5510,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[16,356,1628,1627],"yoast_head":"\nLarge Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke<\/title>\n<meta name=\"description\" content=\"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke\" \/>\n<meta property=\"og:description\" content=\"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\" \/>\n<meta property=\"og:site_name\" content=\"Health News Central\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-30T06:36:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2023\/06\/stem-cell.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"730\" \/>\n\t<meta property=\"og:image:height\" content=\"521\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"katcruz\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"katcruz\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\"},\"author\":{\"name\":\"katcruz\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f\"},\"headline\":\"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke\",\"datePublished\":\"2023-06-30T06:36:07+00:00\",\"dateModified\":\"2023-06-30T06:36:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\"},\"wordCount\":509,\"publisher\":{\"@id\":\"https:\/\/healthnewscentral.com\/#organization\"},\"keywords\":[\"health\",\"inflammation\",\"injection\",\"stem cell\"],\"articleSection\":[\"Health\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\",\"url\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\",\"name\":\"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke\",\"isPartOf\":{\"@id\":\"https:\/\/healthnewscentral.com\/#website\"},\"datePublished\":\"2023-06-30T06:36:07+00:00\",\"dateModified\":\"2023-06-30T06:36:07+00:00\",\"description\":\"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.\",\"breadcrumb\":{\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/healthnewscentral.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/healthnewscentral.com\/#website\",\"url\":\"https:\/\/healthnewscentral.com\/\",\"name\":\"Health News Central\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/healthnewscentral.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/healthnewscentral.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/healthnewscentral.com\/#organization\",\"name\":\"Health News Central\",\"url\":\"https:\/\/healthnewscentral.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png\",\"contentUrl\":\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png\",\"width\":1396,\"height\":484,\"caption\":\"Health News Central\"},\"image\":{\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f\",\"name\":\"katcruz\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g\",\"caption\":\"katcruz\"},\"url\":\"https:\/\/healthnewscentral.com\/author\/katcruz\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke","description":"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/","og_locale":"en_US","og_type":"article","og_title":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke","og_description":"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.","og_url":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/","og_site_name":"Health News Central","article_published_time":"2023-06-30T06:36:07+00:00","og_image":[{"width":730,"height":521,"url":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2023\/06\/stem-cell.jpeg","type":"image\/jpeg"}],"author":"katcruz","twitter_card":"summary_large_image","twitter_misc":{"Written by":"katcruz","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#article","isPartOf":{"@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/"},"author":{"name":"katcruz","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f"},"headline":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke","datePublished":"2023-06-30T06:36:07+00:00","dateModified":"2023-06-30T06:36:07+00:00","mainEntityOfPage":{"@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/"},"wordCount":509,"publisher":{"@id":"https:\/\/healthnewscentral.com\/#organization"},"keywords":["health","inflammation","injection","stem cell"],"articleSection":["Health"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/","url":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/","name":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke","isPartOf":{"@id":"https:\/\/healthnewscentral.com\/#website"},"datePublished":"2023-06-30T06:36:07+00:00","dateModified":"2023-06-30T06:36:07+00:00","description":"In a recent study, just one injection of a patient\u2019s own stem cells to the heart managed to reduce the inflammation.","breadcrumb":{"@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/healthnewscentral.com\/large-trial-of-single-stem-cell-injection-sees-huge-slash-in-risk-of-heart-attack-and-stroke\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/healthnewscentral.com\/"},{"@type":"ListItem","position":2,"name":"Large Trial Of Single Stem Cell Injection Sees Huge Slash In Risk Of Heart Attack And Stroke"}]},{"@type":"WebSite","@id":"https:\/\/healthnewscentral.com\/#website","url":"https:\/\/healthnewscentral.com\/","name":"Health News Central","description":"","publisher":{"@id":"https:\/\/healthnewscentral.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/healthnewscentral.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/healthnewscentral.com\/#organization","name":"Health News Central","url":"https:\/\/healthnewscentral.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/","url":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png","contentUrl":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png","width":1396,"height":484,"caption":"Health News Central"},"image":{"@id":"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f","name":"katcruz","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g","caption":"katcruz"},"url":"https:\/\/healthnewscentral.com\/author\/katcruz\/"}]}},"_links":{"self":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts\/5509"}],"collection":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/comments?post=5509"}],"version-history":[{"count":2,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts\/5509\/revisions"}],"predecessor-version":[{"id":5579,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts\/5509\/revisions\/5579"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/media\/5510"}],"wp:attachment":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/media?parent=5509"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/categories?post=5509"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/tags?post=5509"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}