{"id":4645,"date":"2022-10-26T04:31:56","date_gmt":"2022-10-26T04:31:56","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=4645"},"modified":"2022-10-26T04:31:56","modified_gmt":"2022-10-26T04:31:56","slug":"trial-of-experimental-drug-for-alzheimers-slows-down-mental-decline-by-an-astonishing-27","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/trial-of-experimental-drug-for-alzheimers-slows-down-mental-decline-by-an-astonishing-27\/","title":{"rendered":"Trial Of Experimental Drug For Alzheimer\u2019s Slows Down Mental Decline By An Astonishing 27%"},"content":{"rendered":"
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BioSpace<\/figcaption><\/figure>\n

Biogen<\/a>, an American biotech company, has recently announced the results they obtained from a phase 3 clinical trial that revealed how a new Alzheimer\u2019s drug manged to slow down the rate of cognitive decline for early onset patients by a very inspiring 27%.<\/p>\n

According to the Alzheimer\u2019s Association (AA), the robust study of lecanemab, which happens to be a monoclonal antibody created to clear clumps of amyloid protein from the brain, is \u201cthe most encouraging results in clinical trials treating the underlying causes of Alzheimer\u2019s to date.\u201d<\/strong><\/em><\/p>\n

As for the CEO of the Japanese pharmaceutical company that partnered with Biogen, called Eisai, said the these results of the lecanemab study, which has been named Clarity AD, \u201cproves the amyloid hypothesis, in which the abnormal accumulation of A\u03b2 in the brain is one of the main causes of Alzheimer\u2019s disease.\u201d<\/strong><\/em><\/p>\n

As for Eisai, they believe that these findings will find new pathways and perspective in the diagnosis and treatment of Alzheimer\u2019s disease, while managing to further stimulate innovation in better and newer treatment options.<\/p>\n

The study had 1,800 participants, all diagnosed with early stage Alzheimer\u2019s disease<\/a>, while half of the were given placebo and the other half given twice-weekly infusions of the lacenmab. The study results<\/a> showed that the drug managed to \u2018reduce toxic amyloid plaque in the brain and slow patients\u2019 memory decline, while improving their ability to perform day-to-day tasks.\u2019<\/p>\n

Notably, the full trial analysis has not yet been released.<\/p>\n

As for Alzheimer\u2019s advocates and researchers, they look forward to finding out more about the data during a meeting in November. This will include participant safety and the percentage of parents who experienced any brain swelling as well.<\/p>\n

The AA said in a statement<\/a>, \u201cIf those data are consistent with what we saw today regarding efficacy and safety, we strongly support FDA approval and full [Medicare] coverage.\u201d<\/p>\n

As for Chief Executive Officer at Biogen, Michel Vounatsos, he said, \u201cToday\u2019s announcement gives patients and their families hope that lecanemab, if approved, can potentially slow the progression of Alzheimer\u2019s disease, and provide a clinically meaningful impact on cognition and function.\u201d<\/strong><\/em><\/p>\n

As for the U.S. Food and Drug Administration (FDA)<\/a>, they have agreed that the study results from the 18-month trial can \u2018serve as the confirmatory study to verify the clinical benefit of lecanemab,\u2019 and will announce their decision no later than January 6.<\/p>\n

Although the researchers explain that amyloid is just one component of Alzheimer\u2019s disease, which is why some are saying the benefits that have been measure by this trial are \u201csmall.\u201d<\/p>\n

According to a neurobiologist at the University of Texas who happens to be a sceptic of the amyloid hypothesis explained to NATURE<\/a> journal, how amyloid happens to be \u201cassociated with the problem, but it isn\u2019t \u2018the\u2019 problem.\u201d Moreover, \u201cif you modulate it, of course you can have some small benefit.\u201d<\/p>\n

However, there are other experts that have chimed in with more hopeful statements. For director of research at Alzheimer\u2019s Research UK, Dr. Susan Kohlhaas<\/a>, \u201cThis is a historic moment for dementia research, as this is the first phase 3 trial of an Alzheimer\u2019s drug in a generation to successfully slow cognitive decline.\u201d\u00a0<\/strong><\/em><\/p>\n

\u201cMany people feel Alzheimer\u2019s is an inevitable part of aging. This spells it out: if you intervene early you can make an impact on how people progress,\u201d<\/strong><\/em> she added.<\/p>\n","protected":false},"excerpt":{"rendered":"

Biogen, an American biotech company, has recently announced the results they obtained from a phase 3 clinical trial that revealed how a new Alzheimer\u2019s drug manged to slow down the rate of cognitive decline for early onset patients by a very inspiring 27%. According to the Alzheimer\u2019s Association (AA), the robust study of lecanemab, which […]<\/p>\n","protected":false},"author":9,"featured_media":4646,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[293,621],"yoast_head":"\nTrial Of Experimental Drug For Alzheimer\u2019s Slows Down Mental Decline By An Astonishing 27%<\/title>\n<meta name=\"description\" content=\"Many people feel Alzheimer\u2019s is an inevitable part of aging. 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