{"id":4488,"date":"2022-08-04T03:52:34","date_gmt":"2022-08-04T03:52:34","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=4488"},"modified":"2022-08-04T03:52:34","modified_gmt":"2022-08-04T03:52:34","slug":"scientists-discover-breakthrough-treatment-that-may-be-potential-cure-for-asthma-patients","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/scientists-discover-breakthrough-treatment-that-may-be-potential-cure-for-asthma-patients\/","title":{"rendered":"Scientists Discover Breakthrough Treatment That May Be Potential Cure For Asthma Patients"},"content":{"rendered":"<figure id=\"attachment_4489\" aria-describedby=\"caption-attachment-4489\" style=\"width: 730px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-4489 size-full\" src=\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2022\/07\/asthma.jpeg\" alt=\"\" width=\"730\" height=\"411\" srcset=\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2022\/07\/asthma.jpeg 730w, https:\/\/healthnewscentral.com\/wp-content\/uploads\/2022\/07\/asthma-300x169.jpeg 300w, https:\/\/healthnewscentral.com\/wp-content\/uploads\/2022\/07\/asthma-395x222.jpeg 395w\" sizes=\"(max-width: 730px) 100vw, 730px\" \/><figcaption id=\"caption-attachment-4489\" class=\"wp-caption-text\">Everyday Health<\/figcaption><\/figure>\n<p style=\"font-weight: 400;\">An important breakthrough in treatment for <a href=\"https:\/\/www.cdc.gov\/asthma\/faqs.htm#:~:text=What%20Is%20Asthma%3F,or%20early%20in%20the%20morning.\">asthma<\/a> sufferers has recently been discovered via new research. This could be exactly what the 262 million sufferers around the world need to help them better deal with their respiratory ailment.<\/p>\n<p style=\"font-weight: 400;\">This new study discovered that for those suffering from severe asthma, they actually have a distinct metabolite profile that is detectable in their urine, unlike those that suffer from mild-to-moderate cases of asthma or for otherwise healthy individuals.<\/p>\n<p style=\"font-weight: 400;\">Lead researchers of the study, Dr. Stacey Reinke of <a href=\"https:\/\/www.ecu.edu.au\/\">Edith Cowan University<\/a> in Australia, and Dr. Craig Wheelock of <a href=\"https:\/\/ki.se\/en\">Karolinska Institute<\/a> in Sweden, analyzed urine samples from over 600 study participants over 11 countries \u2013 who were all a part of their U-BIOPRED study \u2013 a Europe-wide initiative to pinpoint and better understand the different sub-types of severe asthma.<\/p>\n<p style=\"font-weight: 400;\">Dr. Reinke shared, <em><strong>\u201cAsthma affects 2.7 million Australians and there were 417 asthma-related deaths in Australia in 2020. To identify and develop new treatment options, we first need to better understand the underlying mechanisms of the disease.\u201d<\/strong><\/em><\/p>\n<p style=\"font-weight: 400;\">They explain that one way to do this is \u2018to examine the body\u2019s chemical profile, or \u2018metabolome,\u2019 which provides a snapchat of a person\u2019s current physiological state and gives useful insight into disease processes.\u2019<\/p>\n<p style=\"font-weight: 400;\">Dr. Reinke added, <em><strong>\u201cIn this case, we were able to use the urinary metabolome of asthmatics to identify fundamental differences in energy metabolism that may represent a target for new interventions in asthma control.\u201d<\/strong><\/em><\/p>\n<p style=\"font-weight: 400;\">What their research team figured out was specific type of metabolite \u2013 called <a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Carnitine-HealthProfessional\/\">carnitines<\/a> \u2013 decreased in those with severe asthma. Carnitines play a vital role by \u2018shuttling fatty acids into mitochondria for energy production.\u2019 While deficiency is rare, foods such as chicken, pork, beef, cod, and milk actually provide people with their carnitine needs.<\/p>\n<p style=\"font-weight: 400;\">Additional studies found that the carnitine metabolism was lower in those with severe asthma. Moreover, they explain that \u201820 different genetic defects involved in fatty-acid metabolism have been identified, some of which impact carnitine production.\u2019<\/p>\n<p style=\"font-weight: 400;\">What these new <a href=\"https:\/\/erj.ersjournals.com\/content\/early\/2021\/11\/04\/13993003.01733-2021.long\">study<\/a> findings will do is help enable researchers to work towards new and more effective therapies for asthmatics, possibly by looking into whether there is a link between genetic defects related to carnitine and severe asthmatics. If such a link is found, then one option for treatment could be a special asthmatic carnitine supplementation.<\/p>\n<p style=\"font-weight: 400;\">As explained by Dr. Reinke, it can be quite difficult and invasive to examine the lungs directly. Thankfully, they have tons of blood vessels.<\/p>\n<p style=\"font-weight: 400;\">She also shared, <em><strong>\u201cTherefore, any biochemical changes in the lungs can enter the blood stream, and then be excreted through the urine. These are preliminary results, but we will continue to investigate carnitine metabolism to evaluate its potential as a new asthma treatment target.\u201d<\/strong><\/em><\/p>\n<p style=\"font-weight: 400;\">\n","protected":false},"excerpt":{"rendered":"<p>An important breakthrough in treatment for asthma sufferers has recently been discovered via new research. This could be exactly what the 262 million sufferers around the world need to help them better deal with their respiratory ailment. This new study discovered that for those suffering from severe asthma, they actually have a distinct metabolite profile [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":4489,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[1211,76,16],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.11 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Scientists Discover Breakthrough Treatment That May Be Potential Cure For Asthma Patients<\/title>\n<meta name=\"description\" content=\"This could be exactly what the 262 million sufferers around the world need to help them better deal with their respiratory ailment.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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