{"id":4315,"date":"2022-06-27T02:08:39","date_gmt":"2022-06-27T02:08:39","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=4315"},"modified":"2022-06-27T02:08:39","modified_gmt":"2022-06-27T02:08:39","slug":"scientists-developed-protein-motors-that-can-drive-themselves-around-wounds-and-kill-bacteria","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/scientists-developed-protein-motors-that-can-drive-themselves-around-wounds-and-kill-bacteria\/","title":{"rendered":"Scientists Developed Protein \u2018Motors\u2019 That Can Drive Themselves Around Wounds And Kill Bacteria"},"content":{"rendered":"
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Times Now News<\/figcaption><\/figure>\n

An engineer in Barcelona has adapted silicon nanobots to that can deliver things to open wounds, such as antibiotics. He even created tiny \u201cmotors\u201d to push the nanobots around.<\/p>\n

Apparently, this is a much faster process for healing than any type of oral, topical, or intravenous administering of antibiotics, for a number of reasons as well. Although the entire idea all seems a bit \u201cscience fiction,\u201d these nanobots could eventually become a part of a medic\u2019s toolkit in the seemingly near future.<\/p>\n

The engineer, Samuel S\u00e1nchez, from the Institute of Bioengineering in Spain, developed these little spheres that can bring cancer drugs or antibiotics throughout a body\u2019s viscous fluids. In fact, he\u2019s already used them to quickly treat infections in mice<\/a>.<\/p>\n

A bioengineer at the University of Pennsylvania, C\u00e9sar de la Fuente, who also lead the project alongside Sanchez, said in an interview with Wired Magazine<\/a>, \u201cWe see that the whole wound gets covered. The machines can actually travel around the wound and clear the infection as they go.\u201d<\/p>\n

One reason why these miniscule bots will be more favorable is because of that \u201cdiffusion,\u201d which is the process where the drugs enter and move around a system normally, normally takes a much longer time in the body\u2019s more viscous fluids, such as mucous.<\/p>\n

More often than not, they are forced to travel to the areas where the fluid in which they\u2019re embedded takes them, leaving the possibility of actually missing the area that is targeted in the first place, or even missing it completely. One example they give is with mucous, where if there is a bacteria or a virus in mucous, when medicine is diffused into the saliva, \u2018it\u2019s normal for the saliva to skirt the edges of the former without every penetrating it, before passing on to other parts of the body.\u2019<\/p>\n

When it comes to the bloodstream, the blood travels all over the body and not just to where they infection is located.<\/p>\n

Creating the \u201cPush\u201d They Needed<\/strong><\/h3>\n

Sanchez knew that these nanobots he created needed propulsion, as to avoid \u2018an artificial form of diffusion.\u2019 He decided to coat the bot\u2019s spherical shaped silica chassis with urease, a protein that converts urea into carbon dioxide and ammonia. He then placed these proteins asymmetrically around the chassis, which meant that whenever they came into contact with urea, the enzymatic reaction that occurred managed to push them \u2018a little bit like an internal combustion engine separating gasoline.\u2019<\/p>\n

According to the report in Wired<\/em>, De la Fuente had been working on new antibiotics taken from protein chains called peptides, which are the type that usually happen in the animal kingdom. He then took one of Sanchez\u2019 chassis and loaded it up with a synthetically-made antibiotic peptide that came from wasp venom, then they dropped it into an infected wound of one of their study mice.<\/p>\n

By rubbing the wound with non-toxic urea, it allowed the nanobots to randomly push themselves around. This resulted in a reduced bacterial content of the infection by 100-1,000 times across the entire open portion of the wound.<\/p>\n

In order to test their nanobots, they also treat cuts in mice with drops of normal antibiotics using bots without the application of the urea, and the outcome was the same reduction in bacterial matter. However, it was only in the area where they were treated and nowhere else.<\/p>\n

Considering the initial success of their experiment with these nanobots, Sanchez and De la Fuente realize that the entire idea seems crazy to think of the possibility of having tiny little machines driving themselves around in people\u2019s bloodstreams.<\/p>\n

De la Fuente shares, \u201cAs scientists, we\u2019re all inspired by science fiction. And I think our job sometimes is to try to get those two worlds closer together. What seems science fiction today, hopefully, in a number of years, becomes reality.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

An engineer in Barcelona has adapted silicon nanobots to that can deliver things to open wounds, such as antibiotics. He even created tiny \u201cmotors\u201d to push the nanobots around. Apparently, this is a much faster process for healing than any type of oral, topical, or intravenous administering of antibiotics, for a number of reasons as […]<\/p>\n","protected":false},"author":9,"featured_media":4316,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[297,16,201,1305],"yoast_head":"\nScientists Developed Protein \u2018Motors\u2019 That Can Drive Themselves Around Wounds And Kill Bacteria<\/title>\n<meta name=\"description\" content=\"An engineer in Barcelona has adapted silicon nanobots to that can deliver things to open wounds, such as antibiotics.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthnewscentral.com\/scientists-developed-protein-motors-that-can-drive-themselves-around-wounds-and-kill-bacteria\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" 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