{"id":3964,"date":"2022-06-16T05:41:44","date_gmt":"2022-06-16T05:41:44","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=3964"},"modified":"2022-06-16T05:41:44","modified_gmt":"2022-06-16T05:41:44","slug":"using-antibiotics-frequently-may-increase-the-risk-of-inflammatory-bowel-disease-for-older-folks","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/using-antibiotics-frequently-may-increase-the-risk-of-inflammatory-bowel-disease-for-older-folks\/","title":{"rendered":"Using Antibiotics Frequently May Increase The Risk Of Inflammatory Bowel Disease For Older Folks"},"content":{"rendered":"
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CTF<\/figcaption><\/figure>\n

Antibiotics are often prescribed for those who suffer from frequent bacterial infections. However, a study has found that the risk of IBD increases for the older population who were had to take multiple rounds of antibiotics. \u201cInflammatory bowel disease, which can easily be overlooked in this age group, should be considered, especially when there\u2019s a history of antibiotic prescriptions,\u201d<\/em><\/strong> lead author of the study said.<\/p>\n

Those who had to frequently take\u00a0antibiotics\u00a0may be at greater risk of developing\u00a0inflammatory bowel disease (IBD). This was found in a research that was presented at\u00a0Digestive Disease Week (DDW) 2022<\/a>. It also must be noted that the study has not been peer-reviewed or published just yet.<\/p>\n

A previous research<\/a> that was published in 2020 had established a link between\u00a0antibiotic\u00a0use and the onset of IBD in the younger generation. Another research was made and this was led by\u00a0Adam Faye, MD,<\/a>\u00a0an assistant professor of medicine and population health at NYU Grossman School of Medicine in New York City. The team wanted to see whether the same connection was applicable for the older generation. They made use of the Danish National Prescription Register and they were able to point out the 2.3 million people aged 60 and older from 2000 to 2018 and assessed the number of antibiotics prescribed, the timing of antibiotics, and the impact of specific antibiotic classes on the chances of developing IBD in the older folks.<\/p>\n

The study took 18 years to complete and during that time, researchers found 10,773 new cases of\u00a0ulcerative colitis\u00a0and 3,825 new cases of Crohn\u2019s. They suggested that constant exposure to antibiotics increased their risk. They also said that environmental factors may play a significant role in developing inflammatory bowel disease for this group.<\/p>\n

\n

\u201cWhen we think of IBD onset, we think of environmental factors and genetic factors as playing a role. So in essence, everything that is not genetically coded is considered an environmental risk factor or exposure [including antibiotic use],\u201d explained Dr. Faye. \u201cIn younger patients, there seems to be a higher genetic risk and thus more of a family history of IBD. In older-onset IBD, family history of IBD is not as strong, suggesting less of a genetic risk, and that environment is playing more of a role to trigger IBD.\u201d<\/p>\n<\/blockquote>\n

\u00a0<\/strong><\/h2>\n

Antibiotic Use Increased the Risk for IBD<\/h3>\n

The increase in the new diagnoses happened when antibiotics were prescribed one to two years before the actual diagnosis. However, it\u2019s also good to note that a high risk remained for prescriptions in the two- to five-year time span before it happened. The link was established for all types of antibiotics. That is, except for nitrofurantoin. This is prescribed for\u00a0those who suffer from urinary tract infections. Antibiotics prescribed for\u00a0gastrointestinal\u00a0infections were the ones most likely connected to the latest IBD diagnosis.<\/p>\n

\u201cInflammatory bowel disease, which can easily be overlooked in this age group, should be considered, especially when there\u2019s a history of antibiotic prescriptions,\u201d<\/strong><\/em> Faye said. He, however, acknowledged that further research must be made to fully establish the connection.<\/p>\n

Limitations of the Study<\/h3>\n

The authors did not collect data on the reason for antibiotic use. For instance, they did not look into if it was prescribed for enteric (intestinal) infections, explained\u00a0Benjamin Cohen, MD<\/a>. He is a gastroenterologist and the clinical director of IBD with the Cleveland Clinic’s Digestive Disease & Surgery Institute. He also wasn\u2019t part of the study. However, he explained, \u201cThe findings should also alert physicians to consider IBD as a reason for new GI symptoms following multiple courses of antibiotics in previous years. This is important because physicians may be hesitant to perform invasive diagnostic procedures in older adults.\u201d<\/p>\n

There are several kinds of antibiotics that can have an effect on the intestinal\u00a0microbiome. This applies to medicines that were utilized to treat other illnesses, explained Faye. \u201cThus, in cases where a mild illness is being empirically treated or is expected to self-resolve in a few days, it may be more prudent to hold off on antibiotics right away.\u201d<\/p>\n

As for what\u2019s to come, Faye’s research team wants to focus their study on exploring the gut microbiome changes that come from antibiotic use. They also want to study if this does play a factor to IBD and how it comes about. They hope to find out more about the connection and supply further evidence for their findings.<\/p>\n

\n

\u201cIf we can determine the microbiome shifts that trigger new-onset IBD in older adults, perhaps there can be a role for\u00a0probiotics\u00a0or other therapies to restore the normal gut flora balance,\u201d he said.<\/p>\n<\/blockquote>\n

Faye also added, \u201cOnce\u00a0inflammation\u00a0is present, treatment needs to focus on controlling the inflammation, which often requires medication therapy. However, there is ongoing research on the role of diet and\u00a0stress\u00a0in maintaining remission.\u201d<\/strong><\/em><\/p>\n

\n","protected":false},"excerpt":{"rendered":"

Antibiotics are often prescribed for those who suffer from frequent bacterial infections. However, a study has found that the risk of IBD increases for the older population who were had to take multiple rounds of antibiotics. \u201cInflammatory bowel disease, which can easily be overlooked in this age group, should be considered, especially when there\u2019s a […]<\/p>\n","protected":false},"author":9,"featured_media":3965,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[125,16,154,156],"yoast_head":"\nUsing Antibiotics Frequently May Increase The Risk Of Inflammatory Bowel Disease For Older Folks<\/title>\n<meta name=\"description\" content=\"Studies find that the risk of IBD increases for the older population who were had to take multiple rounds of antibiotics.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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