{"id":3207,"date":"2022-01-04T05:57:28","date_gmt":"2022-01-04T05:57:28","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=3207"},"modified":"2022-01-04T05:57:28","modified_gmt":"2022-01-04T05:57:28","slug":"an-anti-snoring-device-may-help-improve-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/an-anti-snoring-device-may-help-improve-alzheimers-disease\/","title":{"rendered":"An Anti-Snoring Device May Help Improve Alzheimer\u2019s Disease"},"content":{"rendered":"
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Today in 24 English<\/figcaption><\/figure>\n

Deep sleep is a must. This is when waste products are cleaned from the brain. Included here is the toxic protein called beta-amyloid, which is what\u2019s implicated in Alzheimer\u2019s disease. As researchers have een, those who have disrupted breathing during sleep end up snoring. This is what\u2019s called sleep apnea, and those who suffer from it may not get enough deep sleep.<\/p>\n

What happens when you lack sleep? You\u2019ll notice reduced alertness and poor cognitive performance in the person. And now, experts have associated this with an increased risk for Alzheimer\u2019s disease. In fact, a pilot study has been made and the findings suggest that a device that restores healthy breathing in sleep can also improve cognitive performance in those who suffer from the early stages of Alzheimer\u2019s disease.<\/p>\n

\u00a0<\/strong><\/p>\n

What Happens During Sleep<\/h2>\n

The brain flushes away waste through a network of channels known as the\u00a0glymphatic system. This happens during deep sleep. \u00a0The waste products are toxic proteins such as alpha-synuclein and beta-amyloid. As mentioned previously, these are implicated in\u00a0Parkinson\u2019s disease\u00a0and\u00a0Alzheimer\u2019s disease, respectively.<\/p>\n

However, there\u2019s also a condition that\u00a0health experts call sleep-disordered breathing (SDB). This is when the upper airway of the respiratory tract repeatedly collapses. This has the ability to disrupt the cleansing process that happens during sleep. The mild case causes\u00a0snoring, but the more severe form known as\u00a0obstructive sleep apnea (OSA)\u00a0stops respiration in its tracts for several seconds at a time. The worst part is that respiration halts completely.\u00a0<\/strong><\/p>\n

Sleep apnea prevents people who suffer from it from getting the rest they need. They feel tired and fatigued during waking hours, they experience difficulty concentrating, and they will experience problems with memory.<\/strong> That\u2019s because OSA prevents the brain from entering into the deepest phase of sleep, or what they call slow wave sleep. During this time, the brain\u2019s waste disposal system is\u00a0doing its hardest work.<\/p>\n

<\/h2>\n

A Buildup of Toxic Proteins<\/h2>\n

Studies have connected OSA in the development of\u00a0Alzheimer\u2019s and\u00a0Parkinson\u2019s disease. They say that this may possibly be because of the accumulated toxic proteins that weren\u2019t cleaned. \u201cThere are a number of studies showing that sleep apnea increases one\u2019s risk of developing Alzheimer\u2019s disease,\u201d<\/em><\/strong> explained\u00a0Jean-Paul Wiegand, Ph.D., preclinical program manager at the\u00a0Center for Innovation in Brain Science\u00a0at the University of Arizona Health Sciences in Tucson.<\/p>\n

He spoke to Medical News Today<\/em>\u00a0and said that there is also proof that sleep disturbance can be an early symptom of Alzheimer\u2019s. He spoke, \u201cSleep apnea is a multifaceted contributing factor to [Alzheimer\u2019s disease], as it [affects both] sleep quality \u2014 and, subsequently, the long-term memory consolidation that occurs during restful sleep, as well as amyloid clearance \u2014 and cardiovascular health.\u201d<\/em><\/strong><\/p>\n

There is a study made in 2014 that reported how common treatment for\u00a0sleep apnea\u00a0known as\u00a0continuous positive airway pressure\u00a0can stall cognitive decline in its tracks, thus improving the early symptoms of Alzheimer\u2019s disease. Then, a new study also found how another treatment called\u00a0myTAP can improve respiration patterns during sleep, especially in those who snore. There were clues made in this small pilot study. The researchers saw that the treatment may improve cognitive performance in those with mild cognitive impairment and the said disease.<\/strong><\/p>\n

 <\/p>\n

Reduced Snoring<\/h2>\n

The myTAP<\/strong> is a customized oral appliance. It was designed to snap into place over the teeth. What the device does is push the lower jaw slightly forward. This will ease the breathing through the nose and thus, reduce snoring. Health experts believe that breathing through the nose the brain activity that is very much important when entering deep, or\u00a0slow wave, sleep.<\/p>\n

A team of researchers at the\u00a0Center for BrainHealth, which is part of the University of Texas at Dallas and Texas A&M University, conducted a study with those who snore. The participants were aged 50 to 85 years old. Of those who were at the start of the research, 14 were cognitively healthy, 14 had mild cognitive impairment, and 9 suffered from Alzheimer\u2019s disease.<\/p>\n

For them to get the baseline data, the researchers asked these volunteers to sleep as normal at home. They were asked to bring portable recorders with them in order to measure their\u00a0breathing rate,\u00a0heart rate, and snoring. During the daytime, the researchers made assessments on their memory, executive function, and attention.<\/p>\n

The scientists made some interesting discoveries. The respiration rate, or the number of breaths per minute, that happened during sleep fluctuated significantly more when they compared those who were cognitively healthy to those who suffered from Alzheimer\u2019s disease. Some of them were then asked to use the myTAP device during bedtime for 4 weeks straight. Of these, 5 of them were cognitively healthy, 7 suffered from mild cognitive impairment, and 6 suffered from Alzheimer\u2019s.<\/p>\n

After the four weeks was completed, all of them were observed to have a lower maximum breathing rate. This meant that their sleep quality had very much improved. The improvement was also seen most in those with Alzheimer\u2019s, then in those with mild cognitive impairment, then lastly, in those who were cognitively healthy.<\/strong><\/p>\n

The clinicians also saw improvements in breathing rate fluctuation. It\u2019s good to note, however, that the results seen were not considered statistically significant.<\/p>\n

The researchers also think that if larger studies will confirm their results, their device could help health professionals when they need to diagnose mild cognitive impairment and Alzheimer\u2019s disease, specifically in those who snore.<\/p>\n

\u201cWe saw three distinct patterns amongst the groups of people, meaning we can look for a breathing pattern that might predispose individuals to having dementia,\u201d<\/em><\/strong> shared\u00a0Emet Schneiderman, Ph.D., one of the researchers involved and a professor in the Department of Biomedical Sciences at Texas A&M University College of Dentistry.<\/p>\n

 <\/p>\n

Cognitive Improvements Seen<\/h2>\n

After 4 weeks of treatment, the executive and memory functioning of participants improved significantly especially in those with mild cognitive impairment. They have also seen improvements in some of those with Alzheimer\u2019s.\u00a0Generally, the study was unfortunately too small to identify any statistically significant improvements and changes in cognitive performance in those living with disease.<\/strong><\/p>\n

Still, the researchers believe that a longer period of treatment may be required for them to conclude that they have seen substantial improvements. \u201cIf we can make significant changes for individuals with mild cognitive impairment, we can slow the onset of Alzheimer\u2019s disease,\u201d shared Dr. Namrata Das, Ph.D., MPH, who is a postdoctoral fellow at McLean Hospital, Harvard Medical School, in Belmont, MA., and another researcher on the team.<\/p>\n

The findings and details of the study appear in the journal\u00a0Geriatrics<\/em>.<\/em><\/p>\n

 <\/p>\n

More Work Conducted is Needed<\/h2>\n

The researchers are looking for further funding for a follow-up study. This time, they will incorporate the use of MRI in order to detect possible structural changes happening in the brain with the treatment they\u2019ll apply. This research will also look into possible changes in the blood levels of beta-amyloid and tau, which, as we said, are the toxic proteins linked to Alzheimer\u2019s.<\/strong><\/p>\n

\u201cWe are in the process of applying to [the National Institute on Aging] for a larger study with submission in February 2022 and will integrate MRI scans and blood tests for amyloid beta and tau proteins,\u201d<\/em> <\/strong>ssenior author\u00a0Preetam Schramm, Ph.D., from Texas A&M University College of Dentistry, said in an email exchange with MNT<\/em>.<\/em><\/p>\n

\u201cTreating poor sleep will serve to rescue immediate behavioral deficits of impaired memory consolidation at night, but it will take time to observe whether it alleviates amyloid buildup,\u201d said Dr. Wiegand. He also concluded, \u201cI believe this study is a step in the right direction to attack one of the most pervasive and understudied contributing factors to [Alzheimer\u2019s disease]. Applied early, the effect could be cumulatively beneficial.\u201d<\/p><\/blockquote>\n

The doctor also approached the study cautiously. He said that a combination of treatments may be needed to look into all the underlying causes of Alzheimer\u2019s disease in the brain.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Deep sleep is a must. This is when waste products are cleaned from the brain. Included here is the toxic protein called beta-amyloid, which is what\u2019s implicated in Alzheimer\u2019s disease. As researchers have een, those who have disrupted breathing during sleep end up snoring. This is what\u2019s called sleep apnea, and those who suffer from […]<\/p>\n","protected":false},"author":9,"featured_media":3208,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[282,1045,16,1046],"yoast_head":"\nAn Anti-Snoring Device May Help Improve Alzheimer\u2019s Disease<\/title>\n<meta name=\"description\" content=\"A device that restores healthy breathing in sleep can also improve cognitive performance of those in the early stages of Alzheimer\u2019s disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthnewscentral.com\/an-anti-snoring-device-may-help-improve-alzheimers-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An Anti-Snoring Device May Help Improve 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