{"id":2967,"date":"2021-07-27T03:37:20","date_gmt":"2021-07-27T03:37:20","guid":{"rendered":"https:\/\/healthnewscentral.com\/?p=2967"},"modified":"2021-07-27T03:37:20","modified_gmt":"2021-07-27T03:37:20","slug":"how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system","status":"publish","type":"post","link":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/","title":{"rendered":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System"},"content":{"rendered":"
\"\"
Care2cure Physiotherapy<\/figcaption><\/figure>\n

At this point in time, there are currently no effective treatments for fibromyalgia. What exactly is this? For those unfamiliar with the term, this refers to a chronic condition that causes widespread pain, sleep problems, fatigue, and emotional distress those who suffer from it.<\/p>\n

While doctors and experts have yet to point out what the underlying causes may be, some research has pointed out the fact that the root may stem from the immune system. They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice. This finding strongly suggests that fibromyalgia could actually be an autoimmune disorder. While much has yet to be discovered, this finding could lead to better diagnostic blood tests and more effective treatments for those who suffer from the disease.<\/p>\n

 <\/p>\n

All about Fibromyalgia<\/strong><\/h2>\n

People who suffer from fibromyalgia experience chronic pain and sensitivity to pressure and cold. This happens all over their body. Moreover, they may also experience trouble sleeping, or suffer from fatigue and emotional distress.<\/p>\n

According to the\u00a0Centers for Disease Control and Prevention (CDC), almost 4 million adults in the United States suffer from fibromyalgia. This means that there are around 2 percent of the adult population living with the disease, and according to many estimates,\u00a080 percent\u00a0of those who have the condition are female.<\/p>\n

When it comes to fibromyalgia, there is no cure. Fortunately, there are treatments available, but these are limited to relieving symptoms such as pain relief medication and antidepressants. Doctors also urge those who have it to make lifestyle changes such as making time for physical activity and improving personal sleep habits.<\/p>\n

While the researchers are not quite sure about the causes behind fibromyalgia, there are some clues available that indicates how the immune system might be responsible. For instance, those who have lupus or rheumatoid arthritis, both of which are considered autoimmune disorders, are more likely than others to develop the condition.<\/p>\n

Autoimmune disorders happen when the body\u2019s immune system attacks its own tissues. However, there has been no point-blank evidence that this occurs in fibromyalgia. A research team of scientists at King\u2019s College London and the University of Liverpool, both in the United Kingdom, and the Karolinska Institute in Stockholm, Sweden, now says that many fibromyalgia symptoms happen when the person\u2019s antibodies increase the activity of the body\u2019s pain-sensing nerves. They came up with this conclusion when they injected antibodies from people with fibromyalgia into mice. They noticed that the animals became more sensitive to unpleasant stimuli. They also grew weaker. This evidence was seen when the researchers saw how the mice moved around less.<\/p>\n

Ironically, neither injections of antibodies from healthy controls nor serum from people with fibromyalgia with the antibodies removed had any effect on the rodents. The antibodies attached itself to the cells in the\u00a0dorsal root ganglia. These clusters of neurons send sensory signals from the peripheral nervous system to the central nervous system, This means that the brain and spinal cord get the signal. More details about the research have been featured in\u00a0The Journal of Clinical Investigation.<\/p>\n

 <\/p>\n

Profound Implications<\/strong><\/h2>\n

David Andersson, Ph.D.,\u00a0who was the study\u2019s principal investigator at King\u2019s, talked about the research and said, \u201cThe implications of this study are profound.\u201d<\/em><\/strong> He also said, \u201cEstablishing that fibromyalgia is an autoimmune disorder will transform how we view the condition and should pave the way for more effective treatments for the millions of people affected.\u201d<\/strong><\/em><\/p>\n

Dr. Andreas Goebel, M.Sc., Ph.D.,\u00a0the study\u2019s principal investigator from the University of Liverpool, shared how he expected some cases of fibromyalgia to be autoimmune when he first started the research in the UK. \u201cBut David\u2019s team has discovered pain-causing antibodies in each recruited patient,\u201d he explained. \u201cThe results offer amazing hope that the invisible, devastating symptoms of fibromyalgia will become treatable,\u201d<\/strong><\/em> he further stated.<\/p>\n

More importantly, antibodies from people who have to live with fibromyalgia appear to sensitize\u00a0nociceptors. These said nociceptors are nerves found in the skin. These are in charge of sending pain signals to the brain when they sense and detect extremes of temperature and pressure or when they are exposed to noxious chemicals.<\/p>\n

The mice\u2019s symptoms completely disappeared within 2 to 3 weeks after the injection. They have managed to clear the human antibodies from their systems within that time, which suggests how therapies that selectively reduce antibody levels in the bloodstream could actually work for them.<\/p>\n

Prof. Camilla Svensson, Ph.D.,\u00a0the study\u2019s principal investigator from the Karolinska Institute, said, \u201cThe next step will be to identify what factors the symptom-inducing antibodies bind to.\u201d<\/em><\/strong> She also added, \u201cThis will help us not only in terms of developing novel treatment strategies for [fibromyalgia], but also of blood-based tests for diagnosis, which are missing today.\u201d<\/strong><\/em><\/p>\n

The good news is that therapeutic techniques have already been made available. These were designed to reduce the overall level of antibodies in the bloodstream or to remove specific autoimmune antibodies that are detrimental to health. Alternatively, scientists could also finally come up with drugs that are able to prevent these antibodies from binding to their targets. While developments have yet to be made in this field, it does look optimistic.<\/p>\n

 <\/p>\n

A Word of Precaution<\/strong><\/h2>\n

Des Quinn, the chairman of the charity\u00a0Fibromyalgia Action UK, shared how researchers had debates about this disease. They wondered whether or not fibromyalgia is an autoimmune disorder for years. While the new results were more than welcome, he was still very cautious about its future. He talked to Medical News Today about this and said, \u201cIf these results can be replicated and expanded upon, then the prospect of a biomarker or a new treatment for people with fibromyalgia would be extraordinary.\u201d<\/strong> <\/em>He further stated, \u201cHowever, the results need further confirmation and investigation before the outcomes can be applied universally.\u201d<\/em><\/strong><\/p>\n

Quinn also noted that a diagnostic biomarker is badly needed. That\u2019s because some doctors still consider fibromyalgia a \u201cwastebasket diagnosis.\u201d<\/strong><\/em> This is the term used for a vague, unproven diagnosis that has such a broad definition. However, it is also scientifically meaningless. He explained, \u201cIt would also be interesting to investigate how these findings relate to other symptoms of fibromyalgia \u2014 such as fatigue, sleep disturbance, and cognitive issues \u2014 as fibromyalgia impacts with more than just pain symptoms.\u201d<\/strong><\/em><\/p>\n

At this point in time, the research is still very much far from over. More work needs to be done and while the initial findings are indeed impressive, this needs to be backed by more data in order to get support from those in the medical field.<\/p>\n","protected":false},"excerpt":{"rendered":"

At this point in time, there are currently no effective treatments for fibromyalgia. What exactly is this? For those unfamiliar with the term, this refers to a chronic condition that causes widespread pain, sleep problems, fatigue, and emotional distress those who suffer from it. While doctors and experts have yet to point out what the […]<\/p>\n","protected":false},"author":9,"featured_media":2968,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[4],"tags":[294,852,16,687],"yoast_head":"\nHow Fibromyalgia Is Closely Linked To The Body\u2019s Immune System<\/title>\n<meta name=\"description\" content=\"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System\" \/>\n<meta property=\"og:description\" content=\"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\" \/>\n<meta property=\"og:site_name\" content=\"Health News Central\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-27T03:37:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2021\/07\/Fibromyalgia.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"730\" \/>\n\t<meta property=\"og:image:height\" content=\"487\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"katcruz\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"katcruz\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\"},\"author\":{\"name\":\"katcruz\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f\"},\"headline\":\"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System\",\"datePublished\":\"2021-07-27T03:37:20+00:00\",\"dateModified\":\"2021-07-27T03:37:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\"},\"wordCount\":1126,\"publisher\":{\"@id\":\"https:\/\/healthnewscentral.com\/#organization\"},\"keywords\":[\"disease\",\"fibromyalgia\",\"health\",\"immune system\"],\"articleSection\":[\"Health\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\",\"url\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\",\"name\":\"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System\",\"isPartOf\":{\"@id\":\"https:\/\/healthnewscentral.com\/#website\"},\"datePublished\":\"2021-07-27T03:37:20+00:00\",\"dateModified\":\"2021-07-27T03:37:20+00:00\",\"description\":\"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.\",\"breadcrumb\":{\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/healthnewscentral.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/healthnewscentral.com\/#website\",\"url\":\"https:\/\/healthnewscentral.com\/\",\"name\":\"Health News Central\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/healthnewscentral.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/healthnewscentral.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/healthnewscentral.com\/#organization\",\"name\":\"Health News Central\",\"url\":\"https:\/\/healthnewscentral.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png\",\"contentUrl\":\"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png\",\"width\":1396,\"height\":484,\"caption\":\"Health News Central\"},\"image\":{\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f\",\"name\":\"katcruz\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/healthnewscentral.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g\",\"caption\":\"katcruz\"},\"url\":\"https:\/\/healthnewscentral.com\/author\/katcruz\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System","description":"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/","og_locale":"en_US","og_type":"article","og_title":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System","og_description":"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.","og_url":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/","og_site_name":"Health News Central","article_published_time":"2021-07-27T03:37:20+00:00","og_image":[{"width":730,"height":487,"url":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2021\/07\/Fibromyalgia.jpg","type":"image\/jpeg"}],"author":"katcruz","twitter_card":"summary_large_image","twitter_misc":{"Written by":"katcruz","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#article","isPartOf":{"@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/"},"author":{"name":"katcruz","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f"},"headline":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System","datePublished":"2021-07-27T03:37:20+00:00","dateModified":"2021-07-27T03:37:20+00:00","mainEntityOfPage":{"@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/"},"wordCount":1126,"publisher":{"@id":"https:\/\/healthnewscentral.com\/#organization"},"keywords":["disease","fibromyalgia","health","immune system"],"articleSection":["Health"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/","url":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/","name":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System","isPartOf":{"@id":"https:\/\/healthnewscentral.com\/#website"},"datePublished":"2021-07-27T03:37:20+00:00","dateModified":"2021-07-27T03:37:20+00:00","description":"They saw this when a study found that antibodies from people with fibromyalgia induce symptoms of the disease in mice.","breadcrumb":{"@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/healthnewscentral.com\/how-fibromyalgia-is-closely-linked-to-the-bodys-immune-system\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/healthnewscentral.com\/"},{"@type":"ListItem","position":2,"name":"How Fibromyalgia Is Closely Linked To The Body\u2019s Immune System"}]},{"@type":"WebSite","@id":"https:\/\/healthnewscentral.com\/#website","url":"https:\/\/healthnewscentral.com\/","name":"Health News Central","description":"","publisher":{"@id":"https:\/\/healthnewscentral.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/healthnewscentral.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/healthnewscentral.com\/#organization","name":"Health News Central","url":"https:\/\/healthnewscentral.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/","url":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png","contentUrl":"https:\/\/healthnewscentral.com\/wp-content\/uploads\/2020\/03\/Screen-Shot-2020-03-06-at-6.14.51-AM.png","width":1396,"height":484,"caption":"Health News Central"},"image":{"@id":"https:\/\/healthnewscentral.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/38b633af813eb345a6ed540cc63d452f","name":"katcruz","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/healthnewscentral.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/85d53048a5155d19ec8889113281bc78?s=96&d=mm&r=g","caption":"katcruz"},"url":"https:\/\/healthnewscentral.com\/author\/katcruz\/"}]}},"_links":{"self":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts\/2967"}],"collection":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/comments?post=2967"}],"version-history":[{"count":0,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/posts\/2967\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/media\/2968"}],"wp:attachment":[{"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/media?parent=2967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/categories?post=2967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthnewscentral.com\/wp-json\/wp\/v2\/tags?post=2967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}